Technologies

Our development and production processes are guided by the integrated TTQS system – Truffini Total Quality System, that ensures products are safe, effective, stable and appreciated by end consumers.

Icon TTQS TOTAL QUALITY SYSTEM TRUFFINI

We use innovative and advanced technologies, some of them patented by us, that allow us to produce products that are unique and with particular characteristics:

  • Precise control of the release of active ingredients
  • Product stability over time
  • Improved taste

Innovation is a fundamental value for us at Truffini & Reggè.

Over the years we have developed several advanced technologies for improving production processes and the efficacy of our products.

MATRIX TECHNOLOGIES
Gastroresistant Lipidic
Matrix Tablets T-MatrixLipid
Gastroresistant Lipidic
Matrix Granulation G-Matrix-Lipid
Hydro-Lipophylic Matrix IdrOil-Matrix
Jellifying Fast Release Matrix Jelly-F-Matrix
Hydro-Lipophylic Matrix
T-MatrixLipid
  • Patented technology (EP 1225876)
  • “Physiological” gastroprotection
  • Suitable for swallowable mono and multi-layer tablets
  • Boosts absorption of lipophilic active ingredients
Hydro-Lipophylic Matrix
G-Matrix-Lipid
  • Patented technology (EP 1861075)
  • Physiological actives slow release
  • Effective taste masking
  • Boosts lipophilic actives absorption
  • Suitable for oro-dispersible granulates or tablets
Hydro-Lipophylic Matrix
IdrOil-Matrix
  • Matrix coating of lipophilic components
  • Good to add lipophilic components into tablet
Jellifying Fast Release Matrix
Jelly-F-Matrix
  • Gastro release for jellyfying agent
  • Application for gastric release swallowble tablet
  • Best solution for antireflux products
  • Better compliance compared to gels and chewable tablets
CONTROLLED RELEASE
Gastroresistant Liquid Filled
Capsules Gastro-R-Oilcaps
Gastroresistant Liquid Filled
Capsules Vegan Gastro-R-OilcapsV
Colon Release Liquid Filled
Capsules Colon-Oilcaps
Colon Release Powder Filled
Capsules ColonPW-Caps
Gastroresistant Liquid Filled Capsules
Gastro-R-Oilcaps
  • Enteric coated liquid filled hard capsules
  • The best solution for enteric release of oily actives
  • High bioavailability of lipophilic ingredients
  • No unpleasant reflux
  • Possibility of Vegan version (GastroR-Oilcaps V)
Gastroresistant Liquid Filled Capsules Vegan
Gastro-R-OilcapsV
  • Enteric coated liquid filled hard capsules
  • The best solution for enteric release of oily actives
  • High bioavailability of lipophilic ingredients
  • No unpleasant reflux
  • Possibility of Vegan version (GastroR-Oilcaps V)
Colon Release Liquid Filled
Capsules
Colon-Oilcaps
  • Colonic release liquid and powder filled hard capsules pH depended system
  • Useful for IBS/IBD products
Colon Release Powder Filled Capsules
ColonPW-Caps
  • Colonic release liquid and powder filled hard capsules pH depended system
  • Useful for IBS/IBD products
OROBUCCAL RELEASE
Orobuccal Palatable Acid
System Buffered OroPAS H+
Optimized Orobuccal Release
tablet Oro-F-Release
Fast-Slow Optimized Orobuccal Release Tablet Oro-FS-Release
Effervescent Orobuccal Release Tablet Oro-Eff-Release
Orobuccal Palatable Acid System Buffered
OroPAS-H+
  • The innovative solution for optimizing the taste of granulate on acid active ingredients based
  • The best solution for SAMe taste masking
  • Suitable for sachet, stick pack, ODT and chewable tablet
  • 2019 New Patent Pending ( n: 102019000015192)
Optimized Orobuccal Release tablet
Oro-F-Release
  • Patented technology (EP 2393475)
  • Maximum bioavailability
  • Fast absorption
  • No hepatic first pass
  • Optimal CNS actives delivery
  • Demonstrated efficacy (in-vitro and in-vivo tested)
Fast-Slow Optimized Orobuccal
Release Tablet
Oro-FS-Release
  • Patented technology (EP 1861075)
  • Fast (Orobuccal)-Slow (Enteric) release
  • Maximum bioavailability
  • Demonstrated efficacy (in-vitro and in-vivo tested)
  • Effective taste masking
  • Can be used to minimize actives’ interactions
Effervescent Orobuccal Release
Tablet
Oro-Eff-Release
  • Slightly effervescent tablet for a faster dissolution
  • Same advantages as Oro-F-Release™

SUITABLE FOR:

  • Physiological Slow-Release
  • Sport nutrition, can be taken without water during sport activities
  • Elders, children and people with swallowing problems
  • Good for Saline supplements
  • Supplements with high-dosed components (up to 1 g per tablet)
ADVANCED TECHNOLOGIES
Multilayer Advanced Release
System Tablet MultiArs
Truffini Probiotics System Truffini Probiotics System
Chocolate Coating For
Chewable Tablets Cho-Cover
Health Color System HCS
Multilayer Advanced Release System Tablet
MultiArs
  • Patented technology (EP 1225876)
  • Targeted actives’ ingredients release
  • The best solution to minimize components interactions
  • Slow release layer obtained with T-MatrixLipid™ technology
Truffini
Truffini
  • Strain selection
  • Based on efficacy studies and stability data
  • Optimized formulations and processes
  • Stability studies in partnership with strain manufacturer
  • Possibility of rapid product launch
Chocolate Coating For Chewable Tablets
Cho-Cover
  • Chewable chocolate coated tablet
  • Optimal taste masking
  • Good actives protection
  • Suitable for children and pregnant women
Health Color System
HCS
  • capsules based on the physological effect of colors allows to choose the color synergistic to the products effect
  • 65 color samples created with legally approved, longlasting pigments of proven safety
NEW PACKAGING TECHNOLOGIES
Low Moisture Stick-Pack
Technology Dry-SP-System
Low Moisture Stick-Pack Technology Easy Open Open-SP-System
Powder Multisachet Technology MultiPW-Pack
Low Moisture Stick-Pack Technology
Dry-SP-System
  • Low moisture stick-pack technology
  • Coplanar sealings for optimal protection
  • Optimal solution for hygroscopic components: SAMe, GSH, NAC, Carnitine, etc…
  • Process performed in very low humidity rooms
  • Optimal for probiotics
  • The best solution for probiotics
  • Possible nitrogen fillin
Low Moisture Stick-Pack Technology Easy Open
Open-SP-System
  • Low moisture stick-pack technology
  • Coplanar sealings for optimal protection
  • Optimal solution for hygroscopic components: SAMe, GSH, NAC, Carnitine, etc…
  • Process performed in very low humidity rooms
  • Optimal for probiotics
  • The best solution for probiotics
  • Possible nitrogen fillin
Powder Multisachet Technology
MultiPW-Pack
  • Powder multisachet technology
  • Two different powders in 1 sachet
  • One powder 2/3/4 doses in 1 sachet
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